8 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... #rheumatology #diagnosis ... #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
alopecia Differential ... Diagnosis: • ANCA-associated ... fibromyalgia) • Infections ... effusions • Acute ... #Diagnosis #Rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... , HIV) • Glucocorticoid ... hypogammaglobulinemia #immunology #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... thickening or effusion ... MALT Lymphoma • Lung ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
to exclude are infections ... LFT • ESR • ANA ... ) pattern: antibodies ... SLE) • Urinalysis ... #diagnosis #rheumatology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... Disease: Clinical ... • Dyspnea, • Chest ... Imaging, high res CT ... #differential #
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... • CT: Halo sign ... #Infections #HIV ... #AIDS #pulmonary
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... , such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... inflammatory lesions - interstitial ... #Diagnosis #Rheumatology