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differential management vasculitis autoimmune cardiology classification cvid endocarditis erythematosus hypogammaglobulinemia immunodeficiency lupus mycobacteria myopathy nontuberculous ntm sjogrens variable vasculitides
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... hemolytic anemia) • Systemic ... #hematology #diagnosis
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
MAC pulmonary disease ... Hematologic malignancy ... Disease: Clinical ... Imaging, high res CT ... #infectiousdiseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... fibromyalgia) • Infections ... common • Antihistone ... Chronic B-cell activation ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis: Systemic ... , such as systemic ... vasculitis, and SLE ... Cryoglobulins • HIV ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... as SLE, atherosclerotic ... Nodosa: • PAN most commonly ... inflammatory lesions - interstitial ... #Rheumatology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
, verrucous) - Lung ... • Autoimmune (SLE ... Cerebral > Splenic, Pulmonary ... • Petechiae Immunologic ... Cholesterol emboli syndrome
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Inflammatory Myopathies: Commonly ... lung disease Malignancy ... lung disease • ... lung disease • ... #Myopathy #rheumatology
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