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differential syndrome table activation antinuclear antinxp2 antinxp2dm autoimmune classification connectivetissuediseases dermatology dermatomyositis druginduced lungdisease macrophage myopathy myositis patterns sjogrens vasculitides
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung ... : systemic lupus ... #Comparison #Table ... #Pulmonary #Rheumatology ... #Associations
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #rheumatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lupus erythematosus ... : • Symptoms limited ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
IL-1 and IL-6, ... • Systemic lupus ... lupus erythematosus ... #Management #Hematology ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus Erythematosus ... : Chronic disease ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis: Systemic ... , such as systemic ... lupus erythematosus ... Symptoms (Sx) in ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... lung disease Malignancy ... lung disease • ... lung disease • ... Myositis #Myopathy #rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
• Antibodies targeting ... papules Clinical ... had more severe disease ... was diagnosed in ... #management #rheumatology
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