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amiodarone cvid hematology hypogammaglobulinemia immunodeficiency sjogrens toxicity toxicology variable
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease ... lung disease (GLILD ... Chest CT: • Ground-glass ... #hematology #diagnosis
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Lung Toxicity Summary ... hypersensitivity/immunologic ... respiratory distress syndrome ... #Pulmonary #diagnosis ... #management #Toxicology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management
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