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activetb hematology infectiousdiseases latenttb aids common cvid hiv hypogammaglobulinemia immunodeficiency immunology inflammatory iris lupus macrophage mycobacteria nontuberculous ntm reconstitution systemic
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
rest LTBI (-) Immune ... characteristic features Clinical ... Diagnosis: Latent ... #TB #Diagnosis ... #Management #Treatment
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
rest LTBI (-) Immune ... characteristic features Clinical ... Diagnosis: Latent ... #TB #Diagnosis ... #Management #Treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... context of primary immune ... Chronic B-cell activation ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... [SLE], AOSD) • ... Infection (eg, ... #Syndrome #Diagnosis ... #Management #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... (specifically immune ... #diagnosis #management
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Kansasii: • Mimics TB ... MAC pulmonary disease ... Disease: Clinical ... Imaging, high res CT ... #differential #
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... • CT: Halo sign ... papules, pustules, erythematous ... infiltrates, mimicking TB ... #AIDS #pulmonary
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... worsening of that disease ... initiation Clinical ... #Differential # ... Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... , such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... inflammatory lesions - interstitial ... Diagnosis #Rheumatology
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