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hematology activation antinuclear common cvid fungal hiv immunodeficiency immunology lupus macrophage mycobacteria mycoses nontuberculous ntm patterns polychondritis prs relapsing renal
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... #rheumatology #diagnosis ... #differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
years Clinical ... Granulomatous lymphocytic interstitial ... lung disease (GLILD ... Chest CT: • Ground-glass ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... alopecia Differential ... Diagnosis: • ANCA-associated ... fibromyalgia) • Infections ... #Diagnosis #Rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
MAC pulmonary disease ... Disease: Clinical ... Imaging, high res CT ... #differential # ... diagnosis #infectiousdiseases
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... • CT: Halo sign ... papules, pustules, erythematous ... #AIDS #pulmonary ... diagnosis #infectiousdiseases
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Auto-antibodies ... confirm DAH, r/o infection ... sparing of the lung ... diagnosis #management ... #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... [SLE], AOSD) • ... Infection (eg, ... Treatment: • Corticosteroids ... #Diagnosis #Management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... five major clinical ... yeast • At risk: AIDS ... ) #Mycoses #InfectiousDiseases ... #Management #Infections
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
: • SLE • RA - ... ○ Tuberculosis ... Nonspecific ↑ ESR, CRP, ANA ... affected tissue Treatment ... #diagnosis #management
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