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management vasculitis antinuclear autoimmune classification cvid erythematosus hematology immunodeficiency immunology infectiousdiseases myopathy myositis patterns systemic variable vasculitides
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
), Sjogren's Syndrome ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #rheumatology #diagnosis ... #differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Granulomatous lymphocytic interstitial ... lung disease (GLILD ... Chest CT: • Ground-glass ... DDX - Other causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... dermatomyositis, Sjogren ... : • Symptoms limited ... Kidney disease common
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... Syndrome Diagnosis ... MALT Lymphoma • Lung ... #Syndrome #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... ) pattern: antibodies ... SLE) • Urinalysis ... Cryoglobulins • HIV ... #diagnosis #rheumatology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... • CT: Halo sign ... #Infections #HIV ... #AIDS #pulmonary
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tenderness → Consider infectious ... lung disease Malignancy ... lung disease • ... lung disease • ... statins - probably caused
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... Nodosa: • PAN most commonly ... often causes arthritis ... inflammatory lesions - interstitial ... #Diagnosis #Rheumatology
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