9 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
lymphoma, B-cell ... solid cancers • Autoimmune ... diseases: SLE++ ... #management #treatment ... #summary #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANAAutoimmune ... context of other symptoms ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... • B cell lymphoma ... LymphomaLung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Pulmonary Disease ... Diagnosis Of NTM ... • Clinical (Symptoms ... Imaging, high res CT ... #Infections #differential
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
(HL) is an uncommon ... History of EBV infection ... (NSHL) - (most common ... #hematology #oncology ... #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Diagnosis: • ANCA-associated ... rheumatologic diseases ... fibromyalgia) • Infections ... Kidney disease common ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
lung disease Malignancy ... , and lymphoma ... lung disease • ... lung disease • ... Myositis #Myopathy #rheumatology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
cartilage in the body (Autoimmune ... cases such as: • SLE ... • Lymphoma • ... Polychondritis #rheumatology ... #diagnosis #management