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Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Behçet Syndrome ... Diagnosis: Systemic ... LFT • ESR • ANA ... , and SLE) • Urinalysis ... differential #diagnosis
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... (SLE), Systemic ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... alopecia Differential ... Diagnosis: • ANCA-associated ... syndrome Arthritis ... #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... and renal abnormalities ... Diagnosis: • Systemic ... • Behcet syndrome ... #Differential #Diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... syndrome (Clinical ... disease) Differential ... #management #signs ... #symptoms #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
• Anti-NXP2 (ANA ... -1 antibodies (ANA ... lung disease • ... lung disease • ... differential #diagnosis