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syndrome activation antibodies common cvid differential hypogammaglobulinemia igg4 immunodeficiency immunology lupus macrophage patterns sjogrens variable workup
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... (SLE), Systemic ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #patterns #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Clinical history ... #Disease #diagnosis ... #management #phenotypes ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... Differential Diagnosis ... fibromyalgia) • Infections ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... [SLE], AOSD) • ... Infection (eg, ... #Management #Hematology ... #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
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