7 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (SLE), Sjogren's ... : Lupus (SLE), Systemic ... Arthritis, Sjögren ... #Antibodies #ANA
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... : Systemic rheumatic ... as systemic lupus ... LFT • ESR • ANA ... , and SLE) • Urinalysis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
DDX: • ANCA (Antineutrophil ... lupus erythematosus ... (SLE), rheumatoid ... arthritis, Sjögren's ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... : • ANCA-associated ... vasculitis, rheumatoid ... • (-) ANA + (+ ... #Systemic #Lupus
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis: • Systemic ... rheumatic diseases ... , such as SLE, atherosclerotic ... often causes arthritis ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
(SLE) - Antinuclear ... ACE level, CXR, ANCA ... multiple myeloma) • ANA ... #Disease #Rheumatoid ... #testing #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... 7%, Cryoglobulinemia ... Arthritis Malignancy ... #Syndrome #Rheumatology