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vasculitis classification antibodies cryoglobulinemia cryoglobulins erythematosus inflammatory iris lupus patterns polychondritis reconstitution relapsing systemic types vasculitides
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... ), Sjogren's Syndrome ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... : • Clinical triad ... • Autoimmune diseases ... syndrome - type ... #rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... Syndrome Diagnosis ... #Syndrome #Rheumatology ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... , such as SLE, atherosclerotic ... often causes arthritis ... gut involvement, abdominal ... #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Diagnosis: • ANCA-associated ... dermatomyositis, Sjogren ... fibromyalgia) • Infections ... • Type-I Interferonopathies ... context of primary immune
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... to exclude are infections ... LFT • ESR • ANA ... SLE) • Urinalysis ... #diagnosis #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... worsening of that disease ... Related to the type ... #Differential # ... Diagnosis #Management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
as: • SLE • RA ... Most common • Sjogren ... Antibodies to type ... Nonspecific ↑ ESR, CRP, ANA ... #diagnosis #management
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