9 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
, Mainly in Type ... syndrome - type ... Types: • Type ... arthritis) • Types ... • Type III Often
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... ), Sjogren's Syndrome ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #diagnosis #differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... TYPE IV RTA, TYPE ... nephritis • Distal (Type ... #Syndrome #Rheumatology ... #Diagnosis #Management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
are listed as Type ... Elevation Type ... Nonhypoxic • Type ... #Diagnosis #causes ... #typea #typeb #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis: • Systemic ... , such as SLE, atherosclerotic ... often causes arthritis ... gut involvement, abdominal ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... Diagnosis: Systemic ... to exclude are infections ... SLE) • Urinalysis ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... dermatomyositis, Sjogren ... • Type-I Interferonopathies ... context of primary immune
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... system may react ... worsening of that disease ... Related to the type ... Diagnosis #Management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
as: • SLE • RA ... Most common • Sjogren ... Antibodies to type ... Nonspecific ↑ ESR, CRP, ANA ... #diagnosis #management