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differential management vasculitis bcnie bloodculture classification endocarditis fungal mycobacteria mycoses negative ntm patterns polychondritis relapsing sjogrens vasculitides workup
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... #Antibodies #ANA
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
• Infection with ... special media) • Infection ... antimicrobials, clinical ... Assays for antinuclear ... Diseases Fellows
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Nontuberculous Mycobacteria ... : • Syndrome of ... enzymes, diarrhea, abdominal ... Disease: Clinical ... #infectiousdiseases
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... salivary ducts Clinical ... : • 10%-15% Pulmonary ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- GI tract: abdominal ... to exclude are infections ... ) pattern: antibodies ... SLE) • Urinalysis ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... multiplex • GI tract: Abdominal ... gut involvement, abdominal ... , recent viral infection ... #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... 50% in chronic infection ... 3) Abdominal, ... infection • Cough ... infection (~40%
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cases such as: • SLE ... • Infections ... Bacterial ○ Viral infection ... Anti-Matrilin-1 Ab ○ Antibodies ... Polychondritis #rheumatology
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