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diagnosis hematology hypokalemia potassium agglutinin algorithm anemia cold criticalcare cryoglobulinemia cryoglobulins dermatology disease glomerulonephritis hemolytic hypomagnesemia hypomg magnesium nonpalpable palpable
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... Thrombocytopenia: ITP • Secondary ... purpura - Protein C/ ... #rheumatology #
Hypokalemia - Differential Diagnosis Poor Intake - Starvation - Anorexia GI Losses - Vomiting / NG
NG drainage - Diarrhea ... #Diagnosis #Low ... #Potassium #Table ... #Classification ... #Causes
Shock - Differential Diagnosis by Classification Hypovolemic (Intravascular volume depletion) - Hemorrhagic • Trauma
Shock - Differential ... Diagnosis by Classification ... • Severe diarrhea ... exacerbation (any cause ... #Table #CriticalCare
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... : • PR3-ANCA (C-ANCA ... Glomerulonephritis #Vasculitis ... #differential #
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
losses - Chronic diarrhea ... #Diagnosis #Low ... #Magnesium #Table ... #Classification ... #Causes #Workup
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
temperatures below 37°C ... Type III Often Secondary ... factor level • Low ... diagnosis #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... myeloperoxidase (MPO) - (C-ANCA ... • Complement (Low ... #rheumatology # ... classification
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... AIHA Primary Secondary ... originate from a low-grade ... titer of ≥64 at 4°C ... younger pts) Differential
Causes of Hypokalemia I. Decreased intake A. Starvation B. Clay ingestion II. Redistribution into
Causes of Hypokalemia ... Gastrointestinal loss (diarrhea ... #Hypokalemia #Differential ... #Potassium #Classification ... #Causes
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