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diagnosis management neurology rheumatology syndrome barre oncology achalasia arteritis cell comparison dermatology erythematosus esophageal esophagus gastroenterology gbs gca giantcell gravis
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
complete paralysis of all ... Hands or feet • Pain ... Electrodiagnostic studies - EMG ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g ... diseases (e.g., ... body, but can also ... Malignancies (eg ... #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis is an autoimmune ... Hodgkin lymphoma - Autoimmune ... life-threatening Differential ... Generalized fatigue - ALS ... Serologic and EMG
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... extremity, facial ... Electrodiagnostic studies (Ex EMG ... and cauda equina TREATMENT
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... , parts of the axial ... and lower jaw Treatment ... antiinflammatory properties e.g
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... very remarkable w/differential ... E.g. 80 yo ESR cutoff ... that worsens as ... Treatment of GCA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... Arthritis: • Joint pain
Achalasia Summary Epidemiology: 10 cases per 100,000 individuals Defined by inadequate relaxation of the LES and aperistalsis Primary or
Idiopathic • Viral • Autoimmune ... saliva • Chest pain ... suggest cancer as ... fibers of the LES (eg ... LES pressure (eg
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... substantial muscle pain ... Aldolase levels • EMG ... Polymyositis or ALS ... #differential #
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
presents with pain ... red bone marrow, e.g ... SPB - commonly axial ... Bone marrow Treatment ... Diagnosis #Workup #Hematology
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