11 results
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Immunosuppression (e.g ... : Pain in involved ... diseases (e.g., ... Malignancies (eg ... #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
inflammation (eg ... been reported (eg ... Anti-Smooth Muscle Abs ... Abs (rare) - ... of Hepatitis (eg
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
complete paralysis of all ... Hands or feet • Pain ... Electrodiagnostic studies - EMG ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... extremity, facial ... Electrodiagnostic studies (Ex EMG ... and cauda equina TREATMENT
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis is an autoimmune ... life-threatening Differential ... Generalized fatigue - ALS ... PCB variants of GBS ... Serologic and EMG
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... , parts of the axial ... and lower jaw Treatment ... antiinflammatory properties e.g
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... very remarkable w/differential ... E.g. 80 yo ESR cutoff ... that worsens as ... Treatment of GCA
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... Arthritis: • Joint pain
Achalasia Summary

Epidemiology: 10 cases per 100,000 individuals

Defined by inadequate relaxation of the LES and aperistalsis
Primary or
Idiopathic • Viral • Autoimmune ... saliva • Chest pain ... suggest cancer as ... fibers of the LES (eg ... LES pressure (eg
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... substantial muscle pain ... Aldolase levels • EMG ... Polymyositis or ALS ... #differential #