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diagnosis management oncology rheumatology lymphoma achalasia arteritis cell classification comparison dermatology erythematosus esophageal esophagus gastroenterology gca giantcell gravis lupus myasthenia
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g ... : Pain in involved ... diseases (e.g., ... Malignancies (eg ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... hemolytic anemia • Pain ... Immunohistochemical studies (to differentiate ... Lymphoma Treatment ... classification #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
effects of SCC or Hodgkin ... lymphoma - Autoimmune ... life-threatening Differential ... Generalized fatigue - ALS ... Serologic and EMG
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Malignancy (e.g ... Endocrine disorders (e.g ... Arthritis: • Joint pain ... cyclophosphamide) • Hodgkin
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... , parts of the axial ... and lower jaw Treatment ... antiinflammatory properties e.g
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... very remarkable w/differential ... E.g. 80 yo ESR cutoff ... that worsens as ... Treatment of GCA
Achalasia Summary Epidemiology: 10 cases per 100,000 individuals Defined by inadequate relaxation of the LES and aperistalsis Primary or
Idiopathic • Viral • Autoimmune ... saliva • Chest pain ... suggest cancer as ... fibers of the LES (eg ... LES pressure (eg
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... substantial muscle pain ... Aldolase levels • EMG ... : Fever, joint pain ... #differential #
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
presents with pain ... red bone marrow, e.g ... Bone marrow Treatment ... macroglobulinemia • Non-Hodgkin ... Diagnosis #Workup #Hematology
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