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diagnosis differential neurology signs symptoms autoimmune behcet cerebritis erythematosus hematology hemeonc hemophagocytic hlh lupus lymphohistiocytosis manifestations myelitis myopathy myositis neuromyelitis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #neurology #rheumatology ... cerebritis #diagnosis #management
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... (AQP4-lgG disease ... pain • Extra-CNS ... Manifestations #diagnosis #neurology ... #symptoms #signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... nervous system (CNS ... • 8%-27% for CNS ... #Rheumatology # ... Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... tract, and often causes ... chorioretinitis, CNS ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... • Bilateral signs ... MCTD - Bechet disease ... Myelitis #diagnosis #management ... #neurology #differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... nucleotidase 1A (Anti cN ... statins - probably caused
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... caused by uncontrolled ... ▪ Autoimmune diseases ... Presentation • Common Signs ... #Hematology #HemeOnc
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