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anemia hematology hemolytic agglutinin aiha ana antibodies antinuclear cold comparison erythematosus inflammatory lupus management myopathies myopathy myositis patterns sjogrens sle
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Diagnosis Table ... Cold Agglutinin Disease ... #Diagnosis #Table ... #hematology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
exclusion Necrotizing Autoimmune ... Myositis • Onset ... Inflammatory #Myopathies #differential ... #rheumatology # ... table
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... Sjögren Syndrome, Myositis ... Thyroid, Autoimmune ... ANA #patterns #rheumatology ... #diagnosis #differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... nervous system (CNS ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... Sjogrens #Syndrome #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Non-autoimmune ... rheumatologic diseases ... and CNS • Headache ... • Transverse Myelitis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... Viral infection, autoimmune ... CLL (older) • Autoimmune ... pts) Differential ... hemolytic #anemia #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... - Differential ... RP-ILD), dermato-rheumatologic ... #rheumatology # ... differential #diagnosis
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