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differential hematology leukemia management monoclonal paraproteinemias sjogrens vasculitis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... #Rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... develop leukostasis syndrome ... : CNS manifestations ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... affects the skin, neurologic ... cognitive impairment, neurologic ... chorioretinitis, CNS ... #Rheumatology
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