15 results
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
underlying systemic disease ... • Yellow Nail Syndrome ... Onycholysis • Transverse ... fingernail #pathology #differential ... dermatology #nails #table
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
underlying systemic disease ... • Yellow Nail Syndrome ... Onycholysis • Transverse ... fingernail #pathology #differential ... dermatology #nails #table
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Scleromyxedema (CNS ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... meningitis), MCC CNS ... ) Differential Diagnosis ... collaboration • CNS ... #diagnosis #management
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... #treatment #hematology ... #differential
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Eosinophilic Lung Diseases ... Hypereosinophilic Syndrome ... , wt loss; CV, CNS ... #pulmonary #differential ... diagnosis #comparison #table
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... nervous system (CNS ... #Diagnosis #Management ... #Hematology #Rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... super-antigen mediated disease ... MCTD - Bechet disease ... Myelitis #diagnosis #management ... #neurology #differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... peripheral neuropathy, transverse ... • 8%-27% for CNS ... Rheumatology #Diagnosis #Management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Shrinking lung syndrome ... • May involve PNS ... and CNS • Headache ... neuropathy • Transverse