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diagnosis syndrome behcet disease erythematosus fungal hematology infections infectiousdiseases lupus monoclonal mycoses myelitis oncology paraproteinemias signs sjogrens sle symptoms systemic
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... Behcet disease) Differential ... collaboration • CNS
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... Hypergammaglobulinemic macular ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... Pathophysiology of Transverse ... that results in CNS ... Myelitis #diagnosis #management ... #neurology #differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... #Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... and CNS • Headache ... neuropathy • Transverse
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... affects the skin, neurologic ... cognitive impairment, neurologic ... chorioretinitis, CNS ... #Diagnosis #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... Inhalation of spores ... especially the CNS ... MC: CNS CSF: • ... Fungal #Diagnosis #Management
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