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diagnosis differential hematology activation behcet cryofibrinogenemia cryoglobulins dermatologic gpa lupus macrophage mas monoclonal paraproteinemias polyangiitis rash signs sjogrens sle symptoms
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... • Ulcerated, erythematous ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
, and ocular inflammation ... (Granulomatous ... lupus erythematosus ... differential #diagnosis #rheumatology ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... • Autoimmune diseases ... lupus erythematosus ... diagnosis #types #classification ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
affects the skin, neurologic ... ischemia • Skin: Erythematous ... / ANCA + MPO) Cryoglobulinemic ... , and ocular inflammation ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... Classification: ... , macular, patchy ... Non-autoimmune rheumatologic ... Clinical Features
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... (Cryoglobulinemic ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... Clinical Presentation ... lupus erythematosus ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... skin injury) • Neurologic ... (Clinical Dx). ... #diagnosis #management ... signs #symptoms #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... processes: • Systemic ... ocular thrombi ... Antiphospholipid syndrome ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... salivary ducts Clinical ... 7%, Cryoglobulinemia ... #Rheumatology # ... Diagnosis #Management
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