4 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
• Periorbital heliotrope ... (blue-purple) rash ... • Erythematous rash ... #AntiMDA5 #Dermatomyositis ... #diagnosis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
and clinical findings ... red papules -> Gottron ... Rash - Dysphagia ... #PM #Diagnosis ... Pathophysiology #Signs
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
• Periorbital heliotrope ... (blue-purple) rash ... • Erythematous rash ... shoulders (in a shawl ... #rheumatology #dermatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
rash (Gottron papules ... and Gottron sign ... ) • Shawl sign ... • Heliotrope • ... are elevated < PM