27 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Hemolysis #Hemolytic #Anemia ... #Workup #Hematology ... #Diagnosis *
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
1) DIAGNOSE AIHA ... 2) LOOK FOR a cause ... → Systematic screening ... #diagnosis #management ... #treatment #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... #Causes #Workup ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... Splenomegaly - CTD ... #Differential #Diagnosis ... #hematology #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... • Immunologic Workup ... Positive in 60-80% of cases ... Management #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... autoantibodies that will cause ... permeability Diagnosis ... #neurology #rheumatology ... #cerebritis #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
clubbing Clarkson/Systemic ... neuropathy) • Systemic ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Differential #Diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... result in severe anemia ... immune hemolytic anemia ... #Workup #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(CNS) dysfunction ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
frequently affected systems ... Better call hematology ... you’ll do a good workup ... #Algorithm #workup ... #hematology