23 results
diagnosis management oncology differential rheumatology dermatology leukemia causes chronic classification hemophagocytic hlh lymphocytic lymphohistiocytosis acidosis activation agglutinin algorithm anemia antinxp2
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... violaceous, nontender cutaneous ... • Tumor lysis syndrome ... #Leukemia #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... presentation) • Cutaneous ... malignancies -> CLL ... significance (MGUS), CLL ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... gangrenosum • Cutaneous ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
vasculitis) • Cutaneous ... basal ganglia, CNS ... meningitis), MCC CNS ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... Waiting" →several RCTs ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... Leukemia #oncology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... nervous system (CNS ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
scarring • Subacute cutaneous ... Malignancy (e.g. hematologic ... involve PNS and CNS ... vein thrombosis Hematologic ... inflammation Cutaneous
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... skin (xerosis) • Cutaneous ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Rheumatology #
Cutaneous larva migrans skin Rash 25 F recent Caribbean vacation, walked barefoot on sand and now with
CLM most commonly ... No treatment is ... rates of recurrent disease ... effective, and its ... University Infectious Diseases
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