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diagnosis differential hematology classification cryofibrinogenemia cryoglobulins dermatology management monoclonal nonpalpable oncology palpable paraproteinemias purpura sjogrens syndrome types vasculitides
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Vascular Sludging ... hematological disorders ... classification #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
, vascular disorders ... , or other causes ... /HSP • Cryoglobulinemia ... Differential #Diagnosis #hematology ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... pulmonary disease, and ocular ... ulcers, cutaneous, ocular ... Syndrome: - Ocular ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... pulmonary disease, and ocular ... ulcers, cutaneous, ocular ... Cogan syndrome: Ocular
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... Associated Disorders ... pulmonary emboli, and ocular ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Immunotactoid GN & Cryoglobulinemic ... (Cryoglobulinemic ... Hypergammaglobulinemic macular ... Vasculitis) Autoantibodies
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... : • 7%, Cryoglobulinemia ... Sjogrens #Syndrome #Rheumatology
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