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diagnosis endocarditis differential bcnie infective microbiology bacteria bloodculture causes cnie fungal fungi fungus incidence management pathogens staining stains table workup
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
bacilli - Fungi (Candida ... , Aspergillus, Histoplasma ... ) - Culture negative ... streptococci - Culture ... #Differential #InfectiousDiseases
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
negative infective ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... #InfectiousDiseases ... #CNIE #BCNIE #cardiology
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... remain negative ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... differential #workup #infectiousdiseases
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... exceptions are Aspergillus ... • India ink - "Negative ... #microbiology #microscopy ... fungi #fungus #comparison
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Hypercoagulable (APLAS ... • Coagulase-negative ... Tropheryma Whipplei • Aspergillus ... • Blood cultures ... diagnosis #management #cardiology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Hypercoagulable (APLAS ... Negative: • Bartonella ... Tropheryma Whipplei • Aspergillus ... Differential #Diagnosis #cardiology ... #infectiousdiseases
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