5 results
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... #diagnosis #causes ... #BCNIE #cardiology
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
but important causes ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... BCNIE Diagnostic ... #Endocarditis #diagnosis
Important Fungal Stains
Mycology Lab:
 • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... Pathology: • Hematoxylin ... exceptions are Aspergillus ... #microbiology #microscopy ... #staining #diagnosis
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS ... Tropheryma Whipplei • Aspergillus ... Septic Emboli Cause ... Treat underlying cause ... #management #cardiology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential Diagnosis ... Hypercoagulable (APLAS ... Tropheryma Whipplei • Aspergillus ... Treat underlying cause ... #cardiology #infectiousdiseases