10 results
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
Adrenal Insufficiency ... Algorithm Primary ... Adrenal Insufficiency ... #Adrenal #Insufficiency ... #Algorithm #endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Adrenal Insufficiency ... Differential Diagnosis Algorithm ... Weakness, fatigue, nausea ... hyperpigmentation, hypoglycemia ... #endocrinology
Hypoglycemia - Differential Diagnosis Algorithm
Fasting Hypoglycemia:
 • Excess Insulin
 • Medications (e.g. Insulin Secretagogues, ß-Adrenergic Antagonists,
Diagnosis Algorithm ... Idiopathic Other Causes ... Insufficiency ... #endocrinology ... #causes
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Adrenal Insufficiency ... Diagnosis Algorithm ... - Unexplained hypoglycemia ... findings (see algorithm ... Stimulation #StimTest #Endocrinology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Diagnosis and Workup ... pseudohyponatremia • hyperglycemia ... hypothyroidism • adrenal ... insufficiency ... #Algorithm #Nephrology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Insufficiency - ... Differential Diagnosis Algorithm ... #Insufficiency ... #Causes #endocrinology
Causes of Hypothermia - Differential Diagnosis Algorithm
Environmental:
 • Immersion
 • Non-lmmersion
Body Heat Loss:
 • Drugs/ Toxins
Causes of Hypothermia ... Hypothyroidism • Adrenal ... Insufficiency ... • Hypoglycemia ... #causes
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... Diagnosis Algorithm ... unclear (often the case ... #Insufficiency ... Stimulation #Test #Endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Insufficiency: ... aldosterone - Low in cases ... insufficiency. ... diagnosis #testing #endocrinology ... #workup
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 inhibitors work ... minimal chance of hypoglycemia ... patients have renal ... insufficiency. ... Diabetes #DM2 #Endocrinology