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diagnosis causes differential gh growthhormone pediatrics treatment 21hydroxylasedeficiency 21ohd cah comparison congenitaladrenalhyperplasia excess feedbackloop genetics highphosphate hyperphosphatemia management overproduction pituitary
Infographic depicting the main pearls of various types of congenital adrenal hyperplasia for the medical student.
of congenital adrenal ... #CAH #algorithm ... comparison #treatment #Peds ... #Endocrinology ... #Adrenal #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... overgrowth: • Carpal ... signs #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology ... #pathophysiology
Hyperphosphatemia - Differential Diagnosis Algorithm Transcellular Shift: • Rhabdomyolysis • Tumor Lysis • Metabolic or Respiratory Acidosis
Differential Diagnosis Algorithm ... PO4 < 20%: • Renal ... Pseudo-hypoparathyroidism • Acromegaly ... Differential #Diagnosis #Algorithm ... #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... decade → peripheral/acral ... malignancy Pathophysiology ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Tall Stature - Differential Diagnosis Algorithm Normal Growth (BA=CA) • Familial Tall Stature • XYY Syndrome Obese BMI
Differential Diagnosis Algorithm ... Precocious Puberty • Adrenal ... • Congenital Adrenal ... Resistance • Acromegaly ... #endocrinology
Acromegaly Testing Algorithm INDICATIONS FOR TESTING: • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
Acromegaly Testing ... Algorithm INDICATIONS ... enlarged facial or acral ... #Testing #Algorithm ... #diagnosis #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-OHD in the adrenal ... as "congenital adrenal ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
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