6 results
diagnosis betadglucan comparison galactomannan photo aspergillus biomarkers dermatology diseases eosinophilic falsepositives granuloma histoplasmosis laboratory lesions lung majocchis microscopy mouth oral
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
initiation of smoking; Fever ... brown sputum, fever ... , CNS, skin • Infectious ... (Variable) - Fungal ... Diseases #pulmonary #differential
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) ... cut-offs defined in clinical ... differentiate colonization ... non-neutropenic pts, SOT ... setting of GVHD) ID
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
Skin Lesions - Differential ... --> bacterial, fungal ... Pustules + Fever ... Eosinophilic folliculitis ... Skin #Lesions #Differential
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
cut-offs defined in clinical ... surfaces, Albumin, Infections ... >90% (In most clinical ... differentiate colonization ... post-2010 almost never
Oral histoplasmosis in a transplant patient 50 F Midwest hx liver transplant on prednisone MMF fever, sweats,
prednisone MMF fever ... & mimic other infectious ... Other differentials ... Indiana University Infectious ... #mouth #clinical
Majocchi’s Granuloma due to Trichophyton rubrum This is GMS stain and culture of a skin biopsy
No fever. ... Majocchi granuloma in transplant ... Fungal infection ... recommended Mayo Clinic ... Trichophyton #rubrum #clinical
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