23 results
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
Adrenal Insufficiency ... Insufficiency: ... insufficiency ... #Adrenal #Insufficiency ... Workup #Algorithm #endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Adrenal Insufficiency ... insufficiency ... insufficiency ... #Insufficiency ... Diagnosis #Algorithm #endocrinology
Adrenal Insufficiency Algorithm - Cosyntropin Stimulation Test
T-1m: Baseline cortisol drawn
T0: 250 µg cosyntropin given IV
T30m: Repeat
Adrenal Insufficiency ... BCM_InternalMed #Adrenal ... #Insufficiency ... #Stimulation #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Adrenal Insufficiency ... insufficiency) ... insufficiency; ... if > 18, adrenal ... Stimulation #StimTest #Endocrinology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary Adrenal ... Insufficiency - ... leads to limited adrenal ... #Insufficiency ... Pathophysiology #endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Insufficiency - ... Thrombophilia (adrenal ... #Insufficiency ... Algorithm #Causes #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
Adrenal Insufficiency ... BCM_InternalMed #Adrenal ... #Insufficiency ... Diagnosis #Algorithm #endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... indicates normal adrenal ... tertiary AI #Adrenal ... #Insufficiency ... Stimulation #Test #Endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Insufficiency: ... insufficiency. ... Insufficiency: ... insufficiency is ... diagnosis #testing #endocrinology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Insufficiency Addison's ... Insufficiency: ... Primary ovarian insufficiency ... #insufficiency ... addisons #disease #endocrinology