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leukemia rheumatology cll differential lymphocytic autoimmune classification erythematosus hemeonc lupus management mds myelodysplasia myelodysplastic myopathy myositis sle syndromes systemic vasculitides
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... 3) Monoclonal antibodies ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... • Richter’s Syndrome ... #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Malignancy (e.g. hematologic ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... Erythematosus #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... age 70 years Symptoms ... Marrow Failure • Chronic ... #diagnosis #hematology ... #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Eosinophilia, asthma, chronic ... Presentation - Systemic Symptoms ... C-ANCA) pattern: antibodies ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... myopathies Diagnostic ... ANTI-MITOCHONDRIAL MYOPATHY: • Chronic ... muscular atrophy • Chronic ... Myositis #Myopathy #rheumatology
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