822 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... #Syndrome #Pathophysiology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium chloride ... thiazide-sensitive sodium chloride ... • Congenital chloride ... nephrology #management #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Bartter - Gitelman ... • Fatigue Chloride ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... syndrome • Urine Chloride ... krithicism #Gitelman
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Algorithm Urine chloride ... < 20 mmol/l - Chloride ... responsive (Chloride ... > 20 mmol/l - Chloride ... Bartter's Syndrome, Gitelman's
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Alkalosis - Urinary Chloride ... suction, Congenital chloride ... Bartter syndrome, Gitelman ... use The urine chloride ... Urine chloride is
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Algorithm - Urinary Chloride ... suction, Congenital chloride ... Bartter syndrome, Gitelman ... causes #urinary #chloride
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
thiazide-sensitive sodium chloride ... channel, and the chloride–bicarbonate ... #Pathophysiology
Causes of Metabolic Alkalosis - Differential Diagnosis
Chloride depletion syndromes
 • Gastrointestinal losses
    -
Differential Diagnosis Chloride ... syndrome - Gitelman