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diagnosis alkaline alp cancer elevation erythematosus gastroenterology hepatology lupus management phosphatase primary rheumatology sclerosing sle surveillance systemic
Primary sclerosing cholangitis (PSC) - Malignancy Screening and Surveillance Recommendations Cholangiocarcinoma - Annual US or
(PSC) - Malignancy ... - Annual US or MRCP ... months +/- AFP CRC ... - IBD - Colonoscopy ... #PSC #Malignancy
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Leukocytes • Malignancy ... Most common ... Primary biliary Cholangitis ... (PBC) - Other ... Infiltrative diseases - PSC
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Infections • Malignancy ... Antiribosomal P, APLA, PAC ... titers > 1:80 • CBC ... Kidney disease common
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