216 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... pathophysiology #pbc ... #psc #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... stone, Malignancy, PBC ... injury #hepatitis #differential ... #diagnosis #algorithm
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Malignancy, 1° PBC ... Hepatitis, TB Cholestatic ... #Injury #Differential ... Causes #Acute #algorithm
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... dz Cholestatic ... Ducts - PBC
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... biliary Cholangitis (PBC
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... in pregnancy - Cholestatic ... hepatology #diagnosis #differential ... #algorithm
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Hepatocellular and Cholestatic ... Hepatocellular or Cholestatic ... R ≤ 2 = Cholestatic ... Hepatocellular #Cholestatic ... Transaminitis #diagnosis #differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
RNA • R < 2: Cholestasis ... Obstruction: Cholestasis ... epithelia - Cholestasis ... ALT: typical of cholestatic ... chemistry #diagnosis #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
bile ducts causes cholestasis ... → Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... , Intrahepatic cholestasis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... Diabetes Mellitus Liver ... Tests/Enzymes: • Cholestatic ... liver disease ... Hyperthyroidism CBC