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algorithm lfts obstetrics pregnancy biliary causes chemistry chronic failure fatty gastroenterology injury interpretation liverenzymes obgyn pathophysiology pbc primary rvalue transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
disease, liver ... Alcohol-Associated Hepatitis ... (DILI) Viral Hepatitis ... #Cirrhosis #Hepatology ... #diagnosis
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... #hepatitis #comparison ... #differential # ... diagnosis #icp # ... HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... , HELLP Moderate ... • Cholestatic disease ... • Alcoholic hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Autoimmune: Autoimmune hepatitis ... Chronic viral hepatitis ... #injury #hepatitis ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... viral hepatitis ... ALF): • Liver ... Chronic viral hepatitis ... #differential #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... infiltration) Differential ... Hepatitis, Preeclampsia ... , HELLP, Intrahepatic ... Pregnancy #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
/Liver failure ... obstruction • ALP ... bile ducts Differential ... Viral hepatitis, ... #hepatology
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