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diagnosis activation algorithm common cvid gap globulin hodgkins hypogammaglobulinemia immunodeficiency immunology lymphoma macrophage mas mds myelodysplasia myelodysplastic naildisorders protein proteingap
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
discoloration) • Liver ... cirrhosis • Congestive ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
with leukopenia, anemia ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Liver diseases ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
vasculitis: 10%-16% Liver ... primary biliary cirrhosis ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunohistochemical studies (to differentiate ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #hematology #oncology ... #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Sarcoidosis) • Liver ... disease: Cirrhosis ... gastric tumors • Hematology ... #diagnosis #hematology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
- Hepatic cirrhosis ... cell lymphoma Pathophysiology ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management ... #rheumatology #
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