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diagnosis common cvid gap globulin hodgkins hypogammaglobulinemia immunodeficiency immunology mds myelodysplastic protein proteingap sjogrens syndromes tafro thrombocytopenia variable
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... factor (GCSF) treatments ... blood count with differential ... treatment (examples ... #hematology #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
vasculitis: 10%-16% Liver ... primary biliary cirrhosis ... • B cell lymphoma ... #Rheumatology # ... Diagnosis #Management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Liver diseases ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunohistochemical studies (to differentiate ... number of sites of disease ... Treatment • Early ... #hematology #oncology ... #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Sarcoidosis) • Liver ... disease: Cirrhosis ... gastric tumors • Hematology ... anemia • Other ... #diagnosis #hematology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
- Hepatic cirrhosis ... large B cell lymphoma ... Pathophysiology ... Hypoalbuminemia Treatment ... #rheumatology #
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