18 results
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Nonalcoholic fatty liver ... (Budd-Chiari syndrome ... #Differential # ... Hepatology #Cirrhosis ... #Causes
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Clues to non-cirrhotic ... INR, bilirubin, albumin ... /acute hepatitis ... #Diagnosis #causes ... #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
liver disease ( ... hepatitis) - 80% ... Fitz-Hugh-Curtis syndrome ... Failure, Pancreatic, Biliary ... #Diagnosis #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... Cirrhosis #Hepatomegaly ... #Causes #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Causes
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... obstruction, HELLP Syndrome ... #Diagnosis #Causes ... Acute #algorithm #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Diagnosis High ... >1.1 g/dl): - Cirrhosis ... - Alcoholic hepatitis ... Tuberculosis - Biliary ... #Diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... bile ducts Differential ... Viral hepatitis, ... #workup #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Production: • Albumin ... : < 1 • Cirrhosis ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Hepatic: • Cirrhosis ... • Infiltrative disease ... • Acute liver ... failure • Primary biliary ... #Hepatology #causes