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Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Class I agents ... Channel Blockers⠀ Class ... agents in this class ... beta blockers.⠀ Class ... Channel Blockers Class
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
: CLASS 1 - Sodium ... duration: - CLASS ... duration - CLASS ... 1C: Strong Blockade ... & AP duration CLASS
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Eric Strong @DrEricStrong ... - Strong Medicine ... Channel #Blockers #ClassI ... #pharmacology #table ... #comparison
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
: CLASS 1 - Sodium ... duration - CLASS ... duration - CLASS ... 1C: Strong Blockade ... & AP duration CLASS
Etiologies of Hypoaldosteronism

Hyporeninemic Hypoaldosteronism (Low Renin, Low Aldosterone)
 - Diabetic Nephropathy 
 - NSAIDs
Non-Hyporeninemic Hypoaldosteronism (Normal
Inhibitors - Chronic ... Eric Strong https ... #Aldosterone #Comparison ... #Table #Causes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Chronic diarrhea ... Eric Strong https ... Low #Magnesium #Table ... #Classification ... #Causes #Workup
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Obstruction: Biliary stone ... > 2 • NASH, Chronic ... injury: > 3 • Chronic
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
b) CHF c) CVA ... ASA class If ... event, follow ACC algorithm ... Stable patients ... • <6mo since stroke
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Eosinophilia, asthma, chronic ... tract, and often causes ... Palpable purpura: strong ... • ANA (Suggest CTD ... #rheumatology #classification