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diagnosis management differential criticalcare overview rheumatology shock acidosis cellulitis complications diabetes diabeticfoot elevation erythematosus histiocytosis hypertension idsa igg4 infections infectiousdiseases
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
Pathogenesis and clinical ... accumulates in cells ... Glycosylation - AGE cause ... increasing cytogenetic dysfunction ... • Increased PKC
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... disease Systolic dysfunction ... Diastolic dysfunction ... pulmonary Langerhans cell ... #Differential #Causes
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... progressive organ dysfunction ... specific) COMMON CLINICAL ... Cholangitis - mimics PSC ... complement • Classification
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... death Common Clinical ... #differential #causes ... #classification
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). Mild infection: for
IDSA Algorithm for ... 12 000 or <400 cells ... or those with clinical ... evidence of organ dysfunction ... including those caused
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... death Common Clinical ... #differential #causes ... #classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
e.g., uptake by cells ... of lactate as a clinical ... www.ncbi.nlm.nih.gov/pmc ... a multitude of clinical ... #typea #typeb #classification
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
various tissues, leading ... populations) CLINICAL ... • Endocrine Dysfunction ... marrow: Organ dysfunction ... Birbeck granules (EM
Neurocysticercosis (NCC) Summary Pathogen: Larval stage of Taenia solium Infection: Ingesting undercooked pork containing cysticerci in muscle tissue.
Clinical Course: ... infiltrated with host cells ... calcifications cause ... Classification: ... seizures most common clinical
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Skin Disease Classification ... Angioimmunoblastic T-cell ... mild cognitive dysfunction ... : • Chronic B-cell
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