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rheumatology symptoms dermatology dermatomyositis differential management pathophysiology antimda5 antimda5dm autoimmune behcet colitis criteria gangrenosum gca giantcell infection kawasaki lymphocutaneous myopathy
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... association • M > F Clinical ... response to local skin ... Behcet syndrome (Clinical ... #management #signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... occasional oligoclonal bands ... #Differential #Diagnosis
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
: Clinical Findings ... Edema/erythema on hands ... : - Coronary Arteritis ... - Generalized Skin ... #Symptoms #Vasculitis
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
fingertips ("mechanic’s hands ... severity of the disease ... • Arthralgia/arthritis ... • Mechanic's hands ... #dermatology #diagnosis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
clinical findings ... processes occur in the skin ... dorsum of the hands ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Lymphocutaneous Sporotrichiosis Infection Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis? Lymphocutaneous
wane; diagnosis ... trauma leads to skin ... painless, no systemic signs ... University Infectious Diseases ... #photo #hand
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... = vasculitis vs ... variably: On one hand ... required due to skip
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... the palms of the hands ... Syphilis #Rash #Diagnosis ... #Clinical #Photo
Pyoderma Gangrenosum in Ulcerative Colitis- ...left chest (Panel A) and leg (Panel B). The physical examination
examination revealed skin ... leukocytoclastic vasculitis ... A diagnosis of pyoderma ... #clinical #photo ... ulcerative #colitis #derm
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... Gottron sign) ... DM • CPK 10X ULN ... • Nonerosive arthritis ... • Mechanic's hands
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