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Causes of Hypercalcemia

#Differential #Hypercalcemia #Diagnosis #Causes #Endocrinology
Causes of Hypercalcemia ... #Differential ... #Hypercalcemia ... #Diagnosis #Causes ... #Endocrinology
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... #Causes #differential ... #diagnosis #calcium ... #high #endocrinology
Causes of Hypercalcemia - Differential Diagnosis Algorithm
 • Primary Hyperparathyroidism 
 • Possible Familial Hypocalciuric Hypercalcemia
Causes of Hypercalcemia ... - Differential ... Diagnosis Algorithm ... #Differential # ... #Causes #endocrinology
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... Diagnosis Framework ... other hormonal causes ... #endocrinology
Hypocalcemia - Workup Algorithm

Dr Nikhil Lohiya - NEPHKIDS 2020 @NEPHKIDS1

#Hypocalcemia #Workup #Algorithm #differential #diagnosis #endocrinology #causes
Hypocalcemia - Workup ... @NEPHKIDS1 #Hypocalcemia ... Workup #Algorithm #differential ... #diagnosis #endocrinology ... #causes #calcium
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... Differential Diagnosis ... #Differential # ... Diagnosis #Algorithm ... #causes #endocrinology
Causes of Hypercalcemia due to increased Vitamin D levels
 • The BIG 3:
Causes of Hypercalcemia ... jamiekwillows #Hypercalcemia ... #VitaminD #causes ... #differential # ... diagnosis #endocrinology
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... Jansen disease #Hypercalcemia ... #Causes #Differential ... #Diagnosis #Endocrinology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... Milk-alkali syndrome #Hypercalcemia ... #Causes #endocrinology ... #diagnosis #differential
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... 1) Clinical clues ... BrighamChiefs #Hypercalcemia ... #workup #differential ... #diagnosis #endocrinology