19 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... ischemic pain • Can ... predispose to other orthopedic ... common sites: hip ... , shoulder
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... that can confirm ... Differential Diagnosis ... Giant retinal tears ... signs #symptoms #rheumatology
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Hearing Loss - Differential ... The evaluation should ... include a: • Neurologic ... auditory nerve (CN ... ○ Lyme disease
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... should be obtained ... CRP level: (1) Can ... : HIV test, a rubella ... ANA and RF (if clinical
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
proteins which can ... Cryofibrinogenemia Can ... pulmonary emboli, and ocular ... • TTP, HUS and HIT ... Cryofibrinogenemia #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
proximal muscles of shoulder ... and hip • Muscle ... affects the skin, neurologic ... arterial aneurysms can ... Diagnosis #Rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Mycoplasma, EBV, HIV ... younger pts) Differential ... • Diagnostic Test ... Donath-Landsteiner test
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis infections/year ... characteristic features Clinical ... -> Miliary TB Can ... Tuberculin skin test ... patients should
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
arterial aneurysms can ... well as inner ear ... disease Differential ... retinopathy Lab Tests ... #diagnosis #rheumatology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Brain, Eye, and Ear ... CNS) involvement can ... MRI lesions and clinical ... BEE #Syndromes #neurology ... noninflammatory #differential