10 results
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Acute Purpura Fulminans ... Vibrio, aeromonas, Capnocytophaga ... fulminans secondary to Capnocytophaga ... BIDMC_IDFellows #Capnocytophaga ... #photo
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Skin Rash 40 ... underlying r.f as ... +purpuric rash → ... purpura fulminans ... dermatology #clinical #photo
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
and can appear as ... Maculopapular rash ... Henoch-Schönlein purpura ... #dermatology #rash ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
easy bruising to purpura ... (Petechial or purpuric ... rash) • Heart, ... Fibrin degradation products ... #Rheumatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... maculopapular rash ... Post Transfusion Purpura ... Causes purpura & ... diagnosis #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Post Transfusion Purpura ... Causes purpura & ... Blood products contain ... diagnosis #management #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
of fibrin split products ... • Fibrin split products ... Skin necrosis • Purpura ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Thrombocytopenic Purpura ... but the assay may ... Fibrin degradation products ... Haptoglobin - Low as ... Diagnosis #Workup #Hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura ... diseases, such as ... pts with GCA or as ... , mucositis • Rash ... Differential #Diagnosis #Rheumatology
Levamisole-Adulterated Cocaine
These rashes are typical for the leukocytoclastic vasculitis produced by levamisole exposure.
Levamisole is physically similar
leukocytoclastic vasculitis produced ... - Vasculitis - Purpuric ... Patients may describe ... Clinical #Derm #Rash