9 results
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... and anticoagulants ... #coumadin #heparin ... #warfarin #apaxiban ... pradaxa #xarelto #DOAC
Coagulation Cascade - Actions of Anticoagulants
 • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin
 • Fondaparinux
 • Direct
Coagulation Cascade ... : Rivaroxaban, Apixaban ... K Antagonists: Warfarin ... Inhibitors: Argatroban, Dabigatran ... #Cascade #Anticoagulants
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... clotting #INR #heparin ... #LMWH #NOAC #warfarin ... rivaroxaban #Xarelto #apixaban ... #Eliquis #dabigatran
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Reversal Agents - Warfarin ... PCC (Kcentra) - Heparin ... Protamine sulfate - Dabigatran ... (Praxbind) - Apixaban
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Clearance of Oral Anticoagulant ... Agents Warfarin ... 0% Renal Apixaban ... 25% Renal Dabigatran ... , 35% Renal #DOAC
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
- Pathophysiology ... (e.g. warfarin) ... #Pharmacology #Pathophysiology ... #UFH #DOAC #Dabigatran ... #Apixaban #Rivaroxaban
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
commonly used anti-coagulation ... Molecular Weight Heparin ... Enoxaparin - Warfarin ... Xa inhibitors - Apixaban ... #medications #doac
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
on Coagulation ... Thrombin Time, Ecarin ... Clotting Time Warfarin ... Rivaroxaban Apixaban ... Argatroban Dabigatran
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Coagulation #Cascade ... anticoagulation #anticoagulant ... #Warfarin #Dabigatran ... thrombin #inhibitor #Apixaban ... Rivaroxaban #Edoxaban #heparin