10 results
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... and anticoagulants ... #coumadin #heparin ... #warfarin #apaxiban ... pradaxa #xarelto #DOAC
Coagulation Cascade - Actions of Anticoagulants
 • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin
 • Fondaparinux
 • Direct
Coagulation Cascade ... : Rivaroxaban, Apixaban ... K Antagonists: Warfarin ... #Cascade #Anticoagulants ... anticoagulation #pharmacology
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Management Cheat Sheet: Warfarin ... , Apixaban, Dabigatran ... #DOAC #Management ... #Table #Pharmacology ... #Stop #Perioperative
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... clotting #INR #heparin ... #LMWH #NOAC #warfarin ... rivaroxaban #Xarelto #apixaban ... #Eliquis #dabigatran
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Reversal Agents - Warfarin ... PCC (Kcentra) - Heparin ... (Praxbind) - Apixaban ... #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Agents Warfarin ... 0% Renal Apixaban ... 25% Renal Dabigatran ... , 35% Renal #DOAC ... #Pharmacology #
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
- Pathophysiology ... (e.g. warfarin) ... #Pharmacology #Pathophysiology ... #UFH #DOAC #Dabigatran ... #Apixaban #Rivaroxaban
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
commonly used anti-coagulation ... Molecular Weight Heparin ... Enoxaparin - Warfarin ... Xa inhibitors - Apixaban ... #medications #doac
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... For patients on warfarin ... of Therapy • Dabigatran ... inhibitor) • Apixaban ... Management #Treatment #pharmacology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Coagulation #Cascade ... anticoagulation #anticoagulant ... #Warfarin #Dabigatran ... thrombin #inhibitor #Apixaban ... Rivaroxaban #Edoxaban #heparin